Basics of Mutation Screening by DHPLC | Genetics | Biology

In this article we will discuss about the basics of mutation screening by Denaturing High-Performance Liquid Chromatogra­phy (DHPLC). Introduction to Basics of Mutation by DHPLC: Studies of sequence variation are an integral part of genome research, because of differences in the genomic sequences between individuals. Variations in mammalian genomic sequences occur at an estimated frequency of at least one base [...]