Tag Archives | Molecular Basis

Molecular Basis of Inherited DNA Diseases | Biochemistry

The following points highlight the three main molecular basis of inherited DNA diseases. The molecular basis are: 1. Genetic Diseases 2. Cleavage of DNA into Fragments 3. DNA Cloning. Molecular Basis # 1. Genetic Diseases: The human genome contains DNA with about 3 billion (109) base pairs that encode 50,000 to 100,000 genes located on 23 pairs of chromosomes. The [...]

By |2016-07-30T17:19:29+00:00July 30, 2016|Recombinant DNA Technology|Comments Off on Molecular Basis of Inherited DNA Diseases | Biochemistry
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Molecular Basis of Crossing Over | Cell Division

In this article we will discuss about the molecular basis of crossing over. Any molecular model of crossing over must accommodate the explanation of the following phenomena: (a) Gene conversion, (b) Post-meiotic segregation, (c) Polarized conversion and (d) Negative interference. a. Gene Conversion: It is the unequal recovery of alleles in the region of exchange during genetic recombination in cases [...]

By |2016-07-12T13:51:01+00:00July 12, 2016|Cell Division|Comments Off on Molecular Basis of Crossing Over | Cell Division
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