This category includes alcohols and alkyl halides that act non- specifically as local anaesthetics for certain application. They do not constitute routinely used local anaesthetic agents, and most possess actions in addition to some local anaesthetic activities. i. Ethanol: Ethanol applied to skin and allowed to evaporate acts as a refrigerant. Mucosal applications are irritating due to dehydration, and precipitation [...]
This article throws light upon the seventeen major classical local anaesthetics. They are: 1. Cocaine 2. Procaine 3. Chloroprocaine 4. Tetracaine (Amethocaine) 5. Lidocaine (Lignocaine) 6. Mepivacaine 7. Bupivacaine 8. Hexylcaine 9. Proparacaine (Proxymetacaine) 10. Oxybuprocaine (Benoxinate) 11. Benzocaine (Ethyl Amino Benzoate) 12. Butamben (Butylaminobenzoate) 13. Cinchocaine (Dibucaine) and few others. 1. Cocaine: Local anaesthetic potency is 3 times (range [...]
An Ideal Local Anaesthetic: An ideal local anaesthetic should qualify four principal qualities: it should be selective and effective for action and safe and stable for use. Selective: It should selectively block the function of sensory nerves (reversible paralysis) to produce local analgesia. Effective: It should be effective whether applied topically or upon injection. Onset of action should be rapid. [...]