Mechanism of Induced Muta­genesis | Cell Biology

The following points highlight the three main stages for mechanism of induced mutagenesis. The stages are: 1. Base Analogue Incorporation 2. Base Alteration 3. Distortion of DNA. Stage # 1. Base Analogue Incorporation: Some chemical compounds are sufficiently similar to the nitrogen bases of DNA so that they occasio­nally are incorporated into DNA in place of nor­mal bases, such compounds [...]