The mechanism of humoral immunity is accomplished after interaction of antigen with B-cells, antibody production and antigen-antibody binding. 1. Interaction of antigen with B-cells: The B-cells after production from the stem cells (Fig. 22.8) migrate to lymphoid organs. When antigen interacts and contacts the receptor, the later gets stimulated. The B-cells differentiate into antibody producing cells through three steps: activation, [...]
In this article we will discuss about the humoral immunity of immune response. The immune system protects the body from potentially harmful substances by recognizing and responding to antigens. Antigens are foreign particles, normally large or small molecules on the surface of cells, viruses, fungi or bacteria. Some non-living substances such as toxins, chemicals, drugs and foreign particles can also [...]
In this article we will discuss about the role of antibodies and antigens in humoral immunity. Role of Antibodies: Humoral immunity is antibody-mediated. It protects body from extracellular pathogenic agents by combining with them to form antigen-antibody complex, leading eventually to their elimination. The antibodies play at least in three different ways in this process of elimination of an antigenic [...]