In this article we will discuss about:- 1. Examples of Sex-Linked Genetic Diseases 2. General Rules of the Sex-Linked Genetics 3. Y-Linked Genes. Examples of Sex-Linked Genetic Diseases: i. X-Iinked Recessive Diseases: Hemophilia A and B, color blindness, Duchenne muscular dystrophy. ii. X-linked Dominant Diseases: Vitamin D resistant rickets with hypophosphatemia, some types of ectodermal anidrotic dysplasia, genetic defects of [...]
The most frequent combinations of the X-linked recessive mode of inheritance are as follows: 1. The mother is homozygous and normal (XX); the father is hemizygous and affected (X'Y). (Here X' indicates the chromosome carrying the defective gene and X indicates the normal chromosome). All of the sons of this union will be normal and they will inherit the normal [...]
In this article we will discuss about the dominant and recessive types of autosome-linked genetic diseases. Type # 1. Autosome-Linked Dominant Genetic Diseases: Experimental genetics strictly defines the dominant mode of Inheritance of genetic diseases as the situation in which a single dose of gene is quite sufficient to allow the trait thus governed full expression (Table 11.1). The heterozygote [...]