Types of Homology Dependent Gene Si­lencing | Genetics

Two types of HDGS have been categorised: 1. Transcriptional Gene Silencing (TGS) 2. Post-Transcriptional Gene Silencing (PTGS). Type # 1. Transcriptional Gene Silencing (TGS): Transcriptional gene silencing (TGS) is a gene silencing mechanism in which inactivation of (trans) gene specific RNA synthesis takes place. These are predominently observed in transgenic plants containing multiple copies of homologous transgene or endogenous gene. [...]