The following points highlight the three important examples of transgenic animal. The examples are: 1. Cloning Dolly 2. Transgenic Mice 3. Reporter System. Example # 1. Cloning Dolly: In February 1996, Ian Wilmut and co-workers from the Roslin Institute and PPL Therapeutics, both in Edinburgh, Scotland, reported in Nature journal that they had successfully cloned a sheep from a cell [...]
The following points highlight the three important techniques for genome sequencing. The techniques are: 1. Shotgun Approach for Small Bacterial Genome 2. Sequencing of Mapped Clones for S.Cerevisiae Genome 3. Mapping and Sequencing the Human Genome. Technique # 1. Shotgun Approach for Small Bacterial Genome: The first bacterial sequence to be published, for the 1830 kb genome of the bacterium [...]
The possibility of sequencing an entire chromosome was first discussed in 1982 and the Human Genome Project dates back to 1986. Why this desire for ever longer genome sequences? There are following reasons for this urge: 1. Significance of Knowledge of the Complete Genetic Content of a Genome 2. Access to Important Genes 3. Identification of Genes for Human Diseases [...]