In this article we will discuss about the production of pharmaceutical proteins in transgenic plants. Many pharmaceutical proteins of mammalian origin have been synthesized in plants. These ranges from blood products such as human serum albumin. There is an annual demand of more than 500 tonnes for many of these proteins. In view of their economic feasibility, transgenic plants have [...]
The synthesis of triacyl glycerol in developing oilseeds is generally divided into four stages. Stage I: Synthesis of saturated acyl-ACP by stepwise elongation of acetyl-ACP to steoryl- ACP CoA residue is then condensed to the malonyl ACP, forming acetoacetate ACP. Reduction and dehydration is followed by a second reduction to form acyl-ACP. Each of these reactions is catalysed by type [...]
In this article we will discuss about the genetic approach of molecular farming. One of the key objectives in molecular farming is the production of recombinant proteins at high yields. To accomplish high yield, expression construct must optimise every stages of gene expression, i.e., from transcription to protein stability. For high-level transcription, promoter and poly adenylation site, which are often [...]