In this essay we will discuss about the drugs used for the treatment of hypertension. a. Diuretics: Thiazide diuretics in low doses (e.g. 2.5 mg bendrofluazide) produce a maximal or near maximal blood pressure lowering effect, with very little metabolic disturbances and are considered to be the drugs of first choice because of their safety and benefit in reducing the [...]
In this essay we will discuss about the drugs used for the treatment of malaria. 1. Quinine: It is an alkaloid obtained from the bark of the Cinchona tree and remains the best drug for all complicated malaria, especially chloroquine resistant P. falciparum infection. Pharmacokinetics: Quinine is well absorbed orally, about 70% is bound to plasma proteins and CSF penetration [...]
In this essay we will discuss about the drugs used for lowering LDL cholesterol and triglycerides. 1. Statins (HMG-CoA Reductase Inhibitors): Lovastatin, pravastatin, simvastatin, fluvastatin, atrovastatin and rosuvastatin are the statins having similar mechanism of action and side effects. Statins act by inhibiting cellular cholesterol production, depleting the intracellular pool of cholesterol, and in consequence increasing the expression of LDL [...]