The below mentioned article provides notes on Edward syndrome. Aneuploidy for the autosome in man often produces both physical and mental defects. One well-known condition of 18-trisomy or E- trisomy is a clinical syndrome and the child generally dies before birth. In 1980, Edward and Patau simultaneously discovered a new syndrome associated with the presence of an extra group E [...]
In this article we will discuss about the chromosome theory of inheritance. In order to understand the role played by chromosomes as carriers of hereditary material, we must turn the clock backward to some landmarks in the history of genetics. The earliest records date back to the work of the 18th Century plant hybridisers. One of them Kolreuter had some [...]
The following point highlight the five main types of structural variation in chromosomes. The types are: 1. Deletion or Deficiency 2. Duplications 3. Translocations 4. Inversions 5. B-Chromosomes. Type # 1. Deletion or Deficiency: A deficiency means deletion of a small portion of a chromosome resulting in loss of one or more genes. A deficiency originates from breakage occurring at [...]