In this article we will discuss about the structure and synthesis of telomere. Structure of Telomere: Molecular genetic studies have shown that the telomere consists of several short sequences which are tandemly repeated (Table 8.8). The general formula for the composition of the repeating units in one strand of the telomeres of all the eukaryotes is as follows: 5' Cn [...]
In this article we will discuss about the chemical composition of chromatin. Chromatin is composed of DNA (30-40%), RNA (1-10%) and proteins (50-60%). These constituents vary in different organisms and even in the different tissues of the same species (Table 8.2). Even in the same call, the proportions of DNA, RNA and proteins vary with the stage of cell cycle. [...]
The following points highlight the top four models proposed for chromosome structure. The models are: 1. Molecular Model 2. Multi-Stranded Model or Polyneme Chromosome Model 3. General Chromosome Model 4. Folded Fibre Model. Chromosome Structure: Model # 1. Molecular Model: This model of chromosome structure was proposed by Taylor and coworkers in 1957, 1963 and is based on the semiconservative [...]