In this article we will discuss about the metabolism of sphingolipids, explained with the help of a suitable diagram. Sphingosine results from the condensation of palmityl-coenzyme A with serine. The next step consists in the binding of a fatty acid which gives a ceramide. This ceramide can react either with CDP-choline to form a sphingomyelin, or with UDP-galactose to give [...]
In this article we will discuss about the role of phospholipids. Biological membranes are mainly formed by proteins and lipids. In the latter group of constituents, phosphatides and cholesterol are the quantitatively dominant substances. The physical state of phosphatides varies with the temperature. Between the true liquid state and the solid state, these lipids pass through states in which they [...]
Although substantial progress was made during the last decade, all replication mechanisms in eucaryotes are not yet understood because: (a) Replication is an event which occurs much more rarely than in bacteria. Initiation of replication is therefore highly controlled; this complicates the understanding of this process; (b) The DNA is not naked, in the cell, but in the form of [...]