In this article we will discuss about the meaning of site-specific recombinases of bacteria. During evolution of multiple antibiotic resistance, bacteria seem to have made use of enzymes known as site-specific recombinases. Each type of site-specific recombinase binds with a specific nucleotide sequence in double stranded DNA. When the site is present in each of the two duplex molecules, the [...]
In this article we will discuss about:- 1. Discovery of Transformation 2. Process of Transformation 3. Competence 4. Linkage and Gene Mapping. Discovery of Transformation: The phenomenon was first discovered in 1928 from Griffiths experiment with Diplococcus pneumoniae. As this historical experiment has been instrumental for identification of DNA as a hereditary material. Briefly, when a suspension containing a mixture [...]
In this article we will discuss about the meaning and types of transduction of bacteria. Meaning of Transduction: The transfer of a small part of a bacterial genome from a donor to recipient bacterium through the agency of a bacteriophage is called transduction. It may be general or specialised. In generalized transduction almost any part of the donor's chromosome may [...]