Antimetabolites (With Diagram) | Chemotherapy | Animals

This article provides a note on the antimetabolites, explained with the help of suitable diagrams. Folate: MOA By structure folate consists of a pteridine nucleus. PABA and glutamic acid. These folates are taken up into cell actively and converted in presence of DHFR from FH2 into FH4. FH4 acts as a cofactor in the transfer of single carbon fragment via [...]