In this article, we will discuss about the synthesis of RNA. The process of RNA synthesis is known as transcription. DNA contains information for the synthesis of cell's specific proteins. DNA is located in the nucleoid (prokaryotes) or nucleus (eukaryotes); and protein synthesis occurs in the cytoplasm. DNA does not move to the site of protein synthesis (ribosomes) to directly [...]
Let us make in-depth study of the chemical nature, types of ribonucleic acid (RNA) and also about RNA world. Chemical Nature: RNA is a single stranded mixed polymers of four types of ribotides linked together by 3', 5'- phosphodiester bonds. They are adenylate (AMP), guanylate (GMP), cytidylate (CMP) and uridylate (UMP). RNA is predominantly single stranded nucleic acid. However, it [...]
Read this article to learn about the technical considerations required in the use of RNA interference. In several respects the approaches for silencing gene expression using RNAi methods are similar to those used for antisense DNA-mediated suppression of gene expression. In principle, any cloned gene can be targeted by designing RNA oligonucleotides or RNA-expressing viral vectors with sequences complementary to [...]