Many antibodies and antibody derivatives have been produced in plant systems (Table 16.1) but only seven have reached advanced stages of product development and in main pipeline to achieve commercial status. 1. Avicidin: This is an immunoglobulin G (IgG) produced in corn plants, was the first, to be administered to humans and showed some anti-cancer activity. However, product was withdrawn [...]
One of the important goals of biotechnology is the production of plants with improved quality of nutrition for humans as well as for domestic animals. Improved quality of seed storage proteins by tailoring particular amino acids have major health benefits for humans and economic benefits for poultry industries. In this contrast a major target has been increasing lysine and methionine [...]
In this article we will discuss about the production of recombinant antibodies in transgenic plants. Antibodies are complex glycoproteins that recognise and bind to target antigen with high specificity (Fig. 16.2 or Fig. 16.3). Antibody production is restricted only to animals (mammals). Antibodies are used in diagnosis, prevention and treatment of disease. The productions of antibodies in plants are popularly [...]