In this article we will discuss about the drugs that stimulate uterine contractions. Drug # 1. Prostaglandins (PG): Prostaglandins (PG) are the only autacoids that are used in therapy because of their cytoprotective activity in the GIT mucosa, antiplatelet activity, and uterine stimulant and vasodilator actions. Out of the prostaglandins (D2, E2, F2a and I2) formed; PGE2 and PGI2 exert [...]
After reading this article you will learn about the concept and types of pharmacokinetic models. Concept of Pharmacokinetic Models: Drugs remain in dynamic state within the body and drug events often happen simultaneously. In order to describe a complex biologic system, assumptions are made concerning the movement of drugs. The mathematical models are used to describe the absorption, distribution and [...]
After reading this article you will learn about the role and functions of second messengers. Many hormones, neurotransmitters, autacoids and drugs act on specific membrane receptors, the immediate consequence of which is activation of a cytoplasmic component of the receptor, which may be an enzyme such as adenylate cyclase, guanylate cyclase or activation of a transport systems or opening of [...]