Archive | Centrifugation and Subcellular Fractionation

Centrifugation is a useful means of isolating and purifying cellular components because most organelles and macromolecules differ from one another significantly in size and density (and sometimes also in shape, especially in the case of macromolecules). These properties, as well as the density and viscosity of the surrounding medium, determine the rate at which a specific particle will move when [...]