In this article we will discuss about the metabolism of glycine and serine. They are two non-essential amino acids; as we shall see in the following they are inter-convertible, so that for a long time, one did not know which one was formed first and gave rise to the other. It is now known that it is not the simpler [...]
Some amino acids have been produced in Japan by bacterial fermentation since 1950. Their biosynthesis is now possible by genetically manipulating and physiologically altering the microorganism. Corynebacterium glutamicum and Brevibacterium flavum are involved in the synthesis of L-lysine and L-threonine from a common intermediate, aspartic acid. The regulatory mutants of bacteria produce lysine in sufficient amount. Such bacteria eliminate the [...]
In this article we will discuss about the biosynthesis of various amino acids:- 1. Glutamic Acid Family 2. Aspartic Acid Family 3. α-Alanine, Serine, Glycine and Cysteine 4. Valine and leucine 5. Aromatic Amino Acids: Tyrosine, Phenylalanine, Tryptophan 6. Histidine. 1. Glutamic Acid Family: Glutamic acid is the main pathway for assimilation of ammonia by reductive amination of α-keto glutaric [...]