The genetic disorders can be divided as: Type # 1. Mendelian Disorders: These are mainly determined by alteration or mutation in the single gene. These disorders are transmitted in next generation according to the principle of inheritance and can be studied by pedigree analysis. These can be dominant or recessive. For example, Autosomal dominant disorder are Osteogenesis imperfecta, polycystic kidney [...]
In this article we will discuss about the process of transcription in prokaryotes and eukaryotes. Transcription in Prokaryotes: DNA dependent RNA polymerase is the single enzyme that catalyses the transcription of all types of bacterial RNA. (i) Initiation: RNA polymerase binds to promoter and initiates transcription. It associates transiently with 'initiation factor' (σ) and uses nucleoside triphosphates as substrate, obeying [...]
In this article we will discuss about the genetic code, gene expression and DNA fingerprinting. Genetic Code: Genetic code is the relationship between the sequence of nucleotides on mRNA and the sequence of amino acids in the polypeptide. George Gamow, a physicist proposed that in order to code for all the 20 amino acids, the code should be made up [...]