Let us make an in-depth study of the one-gene one-enzyme hypothesis put forward by Beadle and Tatum. One-Gene One-Enzyme Hypothesis: The hypothesis put forward by Beadle and Tatum (1948) states that a gene controls a structural or functional trait through controlling the synthesis of a specific protein or enzyme formed by the latter. They arrived at this conclusion through the [...]
Let us discuss about the nomenclature and definitions of gene with diagram. Nomenclature of Gene: The word gene was introduced by Johannson in 1909 for a single unit of heredity occupying a specific position (locus) in a chromosome. It was later found that the genes lay in a linear order in the chromosome and were carried along with them to [...]
Let us discuss about the two types of gene expression regulation. The two types of gene expression regulation are: (1) Negative Regulation and (2) Positive Regulation. And also discuss about some important terms used in connection with the regulation of gene expression. Most of the genes of an organism produce specific proteins (enzymes), which, in turn produce specific phenotypes. The [...]