In this article, we propose to discuss the Watson-Crick Model of DNA and biological importance of DNA. DNA is the largest macromolecule that represents the genetic material of the cell. Chemically, DNA is a double helix of two antiparallel polynucleotide chains. Each polynucleotide chain is a linear mixed polymer of four deoxyribotides i.e. deoxyadenylate, deoxyguanylate, deoxycytidylate and thymidylate. Watson-Crick Model [...]
The following seven points will highlight the seven important criteria generally used for the classification of DNA. The seven criteria which are generally used for the classification of DNA include: (1) Number of base pairs per turn (2) Coiling pattern (3) Location (4) Structure (5) Nucleotide sequences (6) Coding and Non-coding DNA and (7) Number of strands. (1) Number of [...]
This article provides a complete guide to DNA microarray. Introduction: A DNA microarray (also commonly known as gene or genome chip, DNA chip, or gene array) is a collection of microscopic DNA spots, commonly representing single genes, arrayed on a solid surface by covalent attachment to chemically suitable matrices. DNA arrays are different from other types of microarray, only in [...]