This article throws light upon the nine applications of animal cell culture. The nine applications of animal cell culture are: (1) Model Systems (2) Toxicity Testing (3) Cancer Research (4) Virology (5) Cell-Based Manufacturing (6) Genetic Counselling (7) Genetic Engineering (8) Gene Therapy and (9) Drug Screening and Development. Application # 1. Model Systems: Cell cultures provide a good model [...]
Read this article to learn about the scale-up process in the animal cell culture system. The scale-up process is divided into two categories. The two categories are: (1) Scale-up in Suspension and (2) Scale-up in Monolayer and also about the monitoring of cell growth in the scale-up process. Scale-Up Process: Scale-up involves the development of culture systems in stages from [...]
Read this article to learn about the general considerations for animal cell culture. The general parameters need to be considered are: (i) Cell Quantitation (ii) Equipment and Medium (iii) pH and Buffer Systems (iv)Oxygen (v) Growth Kinetics (vi) Types of Culture Processes (vii) Other Practical Considerations. In the laboratories, small scale cultures of cells in flasks (usually 1-5 litre volume) [...]