The following points highlight the three main processes involved in the genetic recombination of bacteria. The processes are: 1. Conjugation 2. Transformation 3. Transduction. Process # 1. Conjugation: Lederberg and Tatum (1946) discovered conjugation in E. coli and its detailed studies were made by Woolman and Jacob (1956). Conjugation, is a process by which genetic material is transferred from one [...]
Principles of Genetic Recombination (With Diagram)! Principle # 1. Transformation: In this process only a limited amount of DNA is transferred from one strain of bacterium into the other in solution. It was first observed by Griffith (1928) in Pneumococcus pneumoniae (then called Diplococcus). Evidence for this was obtained in the following experiment by him: The Pneumococcus bacteria has both [...]
Let us make an in-depth study of the genetic recombination. After reading this article you will learn about: 1. Bacterial Recombination 2. Holliday Junction Model 3. Two Holliday Junctions 4. Enzymes of Homologous Recombination and 5. Role of Rec A protein in Homologous Genetic Recombination. Introduction to Genetic Recombination: Recombination of DNA takes place by mutation, exchange of DNA strands [...]