In this article we will discuss about Antibodies:- 1. History of Antibodies 2. The Nature of Antibodies 3. Immunoglobulin G or IgG 4. Kinds of Antibodies. History of Antibodies: Von Behring and Kitasato in Berlin in 19th century recognised antibodies in the blood stream of an immunized animal against tetanus and diphtheria. They observed clumping or agglutination of microorganisms and [...]
Read this article to learn about the types, production, labelling, affinity and avidity of antibodies. Antibody Production: (a) Polyclonal Antibodies: It is possible to produce antibodies which bind to proteins, peptides, carbohydrate and nucleic acids. In general, most immunochemical methods are devised for use with antibodies that recognize proteins and peptides. Choice of species for antibody production depends upon the [...]
Read this article to learn about the production, advantages and limitations of monoclonal antibodies. Antibodies or immunoglobulin's are protein molecules produced by a specialized group of cells called B-lymphocytes (plasma cells) in mammals. The structures, characteristics and various other aspects of immunoglobulin's (Igs) are described elsewhere. Antibodies are a part of the defense system to protect the body against the [...]