Read this article to learn about the first ever mammal clone-Dolly. Dolly, the first ever mammal clone was developed by Wilmut and Campbell in 1997. It is a sheep (female lamb) with a mother and no father. The technique primarily involves nuclear transfer and the phenomenon of totipotency. The character of a cell to develop to different cells, tissues, organs, [...]
Read this article to learn about the process of trans-genesis in large animals. In general, trans-genesis in large animals is more difficult than with mice. There are several factors for the lower efficiency of trans-genesis in large animals. These include less number of eggs they produce and technical difficulties in handling, besides long gestational periods to get the offspring (It [...]
Read this article to learn how the transgenic animals are produced by cloning fetal cells. Fetal cells such as fibroblasts are totipotent. Fetal cell cloning was successfully carried out by some workers to produce transgenic sheep (Polly), transgenic bull calf (Gene) and other animals. Transgenes (foreign genes) can be inserted into the fetal cell genomes to produce desired products by [...]