The following points highlight the six major diseases caused due to errors in nucleic acid metabolism. The diseases are: 1. Lesch-Nyhan Syndrome 2. Hereditary Xanthinuria 3. Orotic Aciduria 4. Hypouricemia 5. Von Gierke's Disease 6. Reye's Syndrome. Errors in Nucleic Acid Metabolism: Disease # 1. Lesch-Nyhan Syndrome: a. This condition is characterized by the complete deficiency of phosphoribosyl transferase, which [...]
Nucleoproteins are conjugated proteins containing nucleic acids and basic protein-like protamine's or histones. In nucleoproteins there are salt-like combination between positively charged basic proteins and negatively charged nucleic acids. Cytoplasm also contains ribonucleoprotein which is found particularly in ribosomes. All living cells contain nucleoproteins and some of the simplest systems, such as viruses, consist entirely of nucleoproteins. Protamine's: 1. These [...]
In this article we will discuss about:- 1. Chemistry of DNA 2. Chromatin 3. Chemistry of RNA 4. Structural Organization of RNA 5. DNA and GENE 6. Biological Importance of Nucleic Acids. Contents: Chemistry of DNA Chromatin Chemistry of RNA Structural Organization of RNA DNA and GENE Biological Importance of Nucleic Acids 1. Chemistry of DNA: a. The four types [...]