In this article we will discuss about the replication of reoviruses. The virus can enter the host cell via a receptor on the cell surface. The receptor is not known but is thought to include sialic acid (haeinagglutination, broad cell tropism), and junctional adhesion molecules (JAMs). Virus particles are internalized and partially uncoated by proteases in the endo-lysosomes/lysosomes in the [...]
In this article we will discus about the classification of animal viruses. Baltimore (2008) classified the animal viruses in the following seven groups according to the relationships between virion, nucleic acid and mRNA transcription Table (17.1). The RNA within the virion is known as plus (+) or sense strand because it acts as mRNA, whereas the newly synthesized RNA which [...]
In this article we will discuss about the entry of adenovirus in host cell through attachment and endocytosis steps. The virus enters into the host cell through the steps as given below: (a) Attachment: Attachment to cells is rather slow and takes several hours to reach a maximum. Viral entry occurs into the two stages. An initial interaction of the [...]