In this article we will discuss about the Mechanism of Protein Synthesis in Prokaryotes and Eukaryotes. Protein synthesis in the cell is conducted by ribosomes that are found attached to the membrane of endoplasmic reticulum and microsomes, as well as in free state in the groundplasm. The main components that take part in protein synthesis at cellular level are: 20 [...]
The following points highlight the three main steps involved in mechanism of protein synthesis. The steps are: 1. Initiation of Protein Synthesis 2. Elongation of Polypeptide 3. Termination of Protein Synthesis. Mechanism of Protein Synthesis: Step # 1. Initiation of Protein Synthesis: (i) Amino Acid Activation: The amino acid (AA) is activated by the enzyme "aminoacylsynthetase", and energy is provided [...]
Control of Protein Synthesis! (i) A Mechanism for the control of protein synthesis by Adenovirus VA RNAI: In the absence of VA RNAI protein synthesis process fails in adenovirus infected HeLa cells. This is due to defective initiation. The defect results from phosphorylation of the initiation factor elF-2 on its alpha subunit. The protein kinase is responsible as the DSRNA-activated [...]