The following points highlight the three main phases of DNA replication in prokaryotes. The phases are: 1. Initiation 2. Elongation 3. Termination. Phase # 1. Replication Initiation: Replication initiation involves the following events: (1) Recognition of origin, (2) DNA melting, i.e., separation of the two strands in the origin region, (3) Stabilization of the single strands, (4) Assembly of primosome [...]
In this article we will discuss about a generalised model of DNA replication in prokaryotes. DNA replication is catalyzed by the enzyme DNA polymerase, and it involves several other proteins/enzyme. The data collected from both in vitro and in vivo studies have been synthesized into a generalized model DNA replication, a brief and simplified description of which is given below [...]
In this article we will discuss about the position of prokaryotes in the living world. Traditionally, the living organisms were placed in two kingdoms, the plants (Plantae) and the animals (Animalia). Leeuwenhoek's discovery of microorganisms and the gradual discovery of large number of diverse microorganisms made it impending to think about creating a third kingdom to accommodate those organisms, because [...]