The following basic properties are known to be essential to make a antigens: 1. Foreign Nature 2. Molecular Size 3. Antigenic Determinants and Cross-Reactivity 4. Molecular Rigidity and Complexity 5. Genetic Factors in the Individual. Property # 1. Foreign Nature: The prerequisite for immunogenicity is that the substance should be foreign to the body of recipient. As a result the [...]
In this article we will discuss about the types and mechanism of allergic reactions. Types of Allergic (hypersensitivity) Reactions: Allergic or hypersensitivity reactions are classified in different ways. It may be humoral or cellular types. The antibody responsible for allergic reactions mainly belongs to IgE isotypes, but IgG isotype also involve in non-IgE mediated allergy like, classical "serum sickness". It [...]
The following points highlight the four main types of diagnoses of allergy. The types are: 1. Case History 2. Skin Testing 3. Provocation Test 4. Diagnosis of Allergy based on Total and Specific IgE Determinations. Type # 1. Case History: The case history holds a central position in allergy investigations. In order to get a comprehensive idea about the source [...]