Here is a list of various macrolide antibiotics. 1. Erythromycin: (i) This macrolide antibiotic was isolated from Streptomyces erythreus, a soil- born organism in 1952. (ii) It consists of two sugars, desosamine and cladinose, which are attached to erythronolide, a macro cyclic lactone. (iii) It is slightly water soluble. (iv) The antibiotic remains more active, in alkaline medium than at [...]
This article throws light upon the three main drugs acting against heart worms. They are: 1. Thiacetarsamide Sodium 2. Dithiazanine 3. Diethylcarbamazine Citrate. Drug # 1. Thiacetarsamide Sodium: It consists of the sodium salt of S, S-diester of p-carbamolydithiobenzene aronous acid with mercaptoacetic acid. The chemical structure is depicted in Fig. 35.5. Therapeutic Effectiveness: After 4 doses of thiacetarsamide adult [...]
After reading this article you will learn about:- 1. Meaning of Fluoroquinolones 2. Classifications of Fluoroquinolones 3. Pharmacological Features 4. Pharmacokinetics 5. Pharmacokinetic Parameters 6. Mechanism of Action 7. Antimicrobial Activity 8. Post -Antibiotic Effect 9. Resistance and Other Details. Contents: Meaning of Fluoroquinolones Classifications of Fluoroquinolones Pharmacological Features of Fluoroquinolones Pharmacokinetics of Fluoroquinolones Pharmacokinetic Parameters Mechanism of Action Antimicrobial [...]