In this essay we will discuss about the drugs used for the treatment of malaria. 1. Quinine: It is an alkaloid obtained from the bark of the Cinchona tree and remains the best drug for all complicated malaria, especially chloroquine resistant P. falciparum infection. Pharmacokinetics: Quinine is well absorbed orally, about 70% is bound to plasma proteins and CSF penetration [...]
In this essay we will discuss about the drugs used for lowering LDL cholesterol and triglycerides. 1. Statins (HMG-CoA Reductase Inhibitors): Lovastatin, pravastatin, simvastatin, fluvastatin, atrovastatin and rosuvastatin are the statins having similar mechanism of action and side effects. Statins act by inhibiting cellular cholesterol production, depleting the intracellular pool of cholesterol, and in consequence increasing the expression of LDL [...]
In this essay we will discuss about the drugs used for the treatment of dyspepsia and gastro-esophageal reflux disease:- 1. Non-Systemic Antacids 2. Systemic Antacid 3. Alginates 4. Surface Anesthetics 5. Acid Release Inhibitors 6. Pro-Kinetic Drugs or Motility Stimulants. 1. Non-Systemic Antacids: Aluminum and magnesium containing antacids are relatively insoluble, very poorly absorbed, longer acting and most suitable for [...]