The process that effectively kills or eliminates transmissible agents (such as fungi, bacteria, viruses, spore forms, etc.) from the surface of equipment, article, food, medication, or biological culture medium is called sterilization. The Sterilization is carried out by the methods according to requirement. The methods are: 1. Moist Heat Sterilization 2. Dry Heat Sterilization 3. Gas Sterilization and Others. Method [...]
Environmental monitoring determines the microbial and particulate content of clean room air and surfaces where manufacturing of sterile and non-sterile pharmaceutical products are undergoing so as to achieve and maintain aseptic conditions. There should be very few viable organisms present in the clean room air. However, operators within the clean room disperse large numbers of skin particles. Many of these [...]
The production of sterile products has special requirements particularly in case of medicines. These products must be produced in conditions that ensure purity. The products must also be free from viable organisms and should have limited or permissible particulate/contaminants. It is thus, important to use the tested procedures meant to manufacture the sterile products. Owing to their special manufacturing requirements, [...]