Genetics of the Haemoglobins | Human Genetics

In this article we will discuss about the normal and abnormal haemoglobins. I. Normal Haemoglobin: Haemoglobin consists of 4 polypeptide (globin) chains each associated with a single haem group. There are 5-6 types of haemoglobins normally present at different stages of life, from zygote to adulthood. The embryonal haemoglobins (HbE) are heterogeneous and designated Gower-1, Gower-2 and Portland. In the [...]