In this article we will discuss about:- 1. Introduction to Skin Toxicity 2. Types of Toxic Effects 3. Effects on Epidermal Adnexa 4. Skin Testing Methods 5. Evaluation of Skin Tests. Introduction to Skin Toxicity: The body of all animals, including humans, is almost entirely covered by a layer termed skin which is usually exposed to a variety of physical [...]
The behavioural tests have been used frequently in pharmacological evaluations of drugs for several years. These tests have only recently been recognized as an essential part of toxicity screening because of belief that behavioural responses of animals have been selected as a measure of toxicity of xenobiotics because of the following reasons: (i) The behaviour of the animals is the [...]
The following points highlight the three main functional tests conducted on animals. The tests are: 1. Respiratory Functional Tests 2. Kidney Functional Tests 3. Assessment of Liver by Liver Functional Test. 1. Respiratory Functional Tests: Tests on these functions are often carried out because of their greater sensitivity than morphological changes and also because of their ability to detect reversible [...]