Tag Archives | Metabolism

Major Inborn Errors of Metabolism

The following points highlight the seven major inborn errors of metabolism. The inborn errors are: 1. Phenylketonuria (PKU) 2. Galactosemia 3. Refsum's Disease 4. Maple-Syrup Urine Disease 5. Fructose Intolerance 6. Von Gierke's Disease 7. Hyperlipidemia. Metabolism: Inborn Error # 1. Phenylketonuria (PKU): PKU occurs due to a defect in the metabolism of amino acid phenylalanine. The affected children show [...]

By |2016-08-06T14:12:54+00:00August 6, 2016|Metabolism|Comments Off on Major Inborn Errors of Metabolism
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Oxidation of Pyruvate to Acetyl-CoA

In this article we will discuss about the Oxidation of Pyruvate to Acetyl-CoA. 1. Pyruvate oxidatively decarboxylated to acetyl-CoA ("active acetate") before en­tering the citric acid cycle. 2. The reaction is catalysed by the multi-enzyme complex consisting of sev­eral different enzymes. This complex is known as pyruvate dehydrogenase com­plex. 3. Pyruvate is decarboxylated in the pres­ence of thiamine pyrophosphate (TPP) [...]

By |2016-07-30T17:20:06+00:00July 30, 2016|Carbohydrate Metabolism|Comments Off on Oxidation of Pyruvate to Acetyl-CoA
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