In this article we will discuss about the technology used and commercial production of monoclonal antibodies. Technology Used in Production of Monoclonal Antibodies: Hybridoma Technology: To overcome the limitations of the use of antiserum, a need of new technique was long felt by the immunologists, and that dream was realized during the recent past with the help of "somatic hybridization" [...]
The following points highlight the eight main types of interaction between antigen and antibody. The types are: 1. Neutralization 2. Immune Complex Formation 3. Opsonization 4. Complement System 5. Antibody-Dependent Cell-Medicated Cytotoxicity (ADCC) 6. Hypersensitivity 7. Autoimmunity 8. Immuno-Deficiencies. 1. Neutralization: Certain antibodies called neutralizing antibodies react with antigen and neutralize them so that they fail to attach on host [...]
The antibody-mediated or humoral immunity is that where the B-lymphocytes synthesize antibodies response to the detection of antigens and these antibodies counteract with those antigens. Antibody-mediated immunity is often referred to as humoral immunity because the antibody molecules flow extracellularly through the blood and other vital body fluids which are called humors in Greek. The precursors of B-lymphocytes, which originate [...]