The following points highlight four important ways by which HIV devastates the immune system. The ways are: 1. Direct killing 2. Apoptosis 3. Destruction of un-infected cells 4. Destruction of immune precursor cells. Way # 1. Direct killing: When a large number of viruses is produced and buds out from the surface of CD4+ T cell surface, the cell membrane [...]
In this article we will discuss about the structure of immunoglobulins, explained with the help of a suitable diagram. Identification of antibodies in the serum protein fraction was demonstrated in the classic experiments of A. Tiselius and E.A. Kabat in 1939. However, the basic structure of —globulin molecule was revealed by Rodney R. Porter and Gerald Edehman in 1950s and [...]
HIV infection can be divided into following different stages:- 1. Acute Primary Infection 2. The Immune System Strikes Back 3. Clinical Latency 4. Clinical Latency. Stage # 1. Acute Primary Infection: Once HIV enters the body, the virus infects a large number of CD4+ T cells and replicates rapidly. During this acute phase of infection, the blood has a high [...]