In this article we will discuss about:- 1. Meaning of Chemotherapeutic Agents 2. General Characteristics of Chemotherapeutic Agents 3. Factors that Influence the Effectiveness. Meaning of Chemotherapeutic Agents: Microbial pathogens grow on and within the body of other living beings and their colonization may lead to disease, disability, and death. Thus the control or destruction of microbial pathogens within the [...]
In this article we will discuss about:- 1. Discovery of Sulfonamides 2. Structure of Sulfonamides 3. Mode of Action 4. Effectiveness. Discovery of Sulfonamides: The discovery of the sulfonamides or sulfa drugs in 1935 by Professor Gerhard Domagk (Fig. 45.1) and his team was a pioneering achievement in the war against infections, for which Domagk received the 1939 Nobel Prize [...]
In this article we will discuss about:- 1. Discovery of Penicillin 2. Structure and Types of Penicillin 3. Antibiotic Spectrum 4. Mechanism of Action. Discovery of Penicillin: The first penicillin discovered by Alexander Fleming in 1929 as a product of fungus Penicillium notatum was the penicillin G. Also, penicillin G became the first clinically effective antibiotic. Even with the use [...]