Klinefelter’s Syndrome: History, Origin and Symptoms | Genetics

In this article we will discuss about:- 1. History of Klinefelter's Syndrome 2. Origin of Klinefelter's Syndrome 3. Symptoms 4. Ascertainment and Phenotype 5. Cytogenetic Findings 6. Frequency. History of Klinefelter's Syndrome: 1. In 1942, Klinefelter, Refenstein and Albright found nine men with small testes, aspermia, elevated urinary gonadotrophins and gynecomastics. These persons were later designated as Klinefelter's syndromic. 2. [...]