In this article we will discuss about:- 1. Meaning of Autoimmune Disease 2. Causes of Autoimmune Disease 3. Treatment. Meaning of Autoimmune Disease: Autoimmunity is a condition characterized by the presence of serum autoantibodies and self-reactive lymphocytes (T-cells). It manifests sometimes when the body loses immune tolerance (body's condition to distinguish its own self-antigens from foreign non-self-antigens and not mounting [...]
In this article we will discuss about the primary and secondary immunodeficiencies seen in humans. Primary Immunodeficiencies: An immunodeficiency that arises from a genetic or developmental defect in the immune system is called a primary immunodeficiency. Such defects are present at birth and become manifest at different stages during development. Most defects affect either the lymphoid (giving rise to B [...]
Immune response recruits and mobilizes a series of effector molecules that induce a localized inflammatory response, which ultimately removes the antigen. This inflammatory response usually does not extensively damage the host tissues. But under certain conditions, the inflammatory response produces deleterious effects, resulting in significant tissue damage or even death; this is termed as hypersensitivity or allergy. Hypersensitive reactions may [...]