In this article we will discuss about the principle of Hardy and Weinberg which requires five assumptions for explaining the equilibrium state of gene and genotype frequency. It was the year 1908, when an English mathematician — G. H. Hardy — and a German physician, W. Weinberg independently discovered the principle concerned with the frequency of alleles in a population, [...]
In this article we will discuss about the examples of genetic linkage in humans. Also learn its clinical applications. 1. Nail-Patella Syndrome and ABO Blood Groups: This genetic linkage has been demonstrated by Reneisck and Lawler (1955). The nail- patella syndrome or hereditary onychosteodysplasia is characterised by a constellation of abnormalities. The nail dystrophy is variable, ranging from a triangular [...]
The following points highlight the top five criteria for genetic polymorphism. They are: 1. Selection 2. Mutation and Mutation Rates 3. Genetic Drift 4. Migration Pressure or Gene Flow 5. Meiotic Drive. Criteria # 1. Selection: Selection is the non-random or selective reproduction of genotypes. The elucidation of the selective forces which may have given rise to any particular polymorphism [...]