Diseases due to Abnormalities in Synthesis of Glycoproteins
The following points highlight the seven major diseases caused due to abnormalities in the synthesis of glycoproteins. 1. Many cancer cells exhibit different profiles of oligosaccharide chains on their surfaces and some of which contribute to metastasis. 2. Carbohydrate-deficient glycoprotein syndrome (CDGS) is caused due to defects in the biosynthesis of N-glycan chains (e.g., due to deficiency of Glc NAC [...]