The below mentioned article provides a note on overlapping genes. It is now becoming apparent that in both prokaryotes and eukaryotes a nucleotide sequence can code for more than one protein. The nucleotide sequence of a gene may be translated into a complete polypeptide chain. Then a part of the same sequence may also code for another protein of a [...]
In this article we will discuss about the determination of DNA sequence. The sequence of bases A, T, G, and C in genes and whole genome can provide useful information for understanding gene structure and organisation, encoded protein and cell behaviour. The first complete nucleotide sequence of an entire viral genome (φX174) was determined in 1977 in the laboratory of [...]
Introduction to Recombinant DNA Technology: Recombinant DNA technology has revolutionised life sciences, opening new vistas for research in molecular biology. It allows genetic manipulation using techniques for synthesizing, amplifying and purifying individual genes from any type of cell. Genomics has emerged as an extension of recombinant DNA technology for high resolution mapping and characterization of whole genomes and gene products [...]