Gene Rearrangements in Light and Heavy Chain DNAs | Microbiology
In this article we will discuss about the gene rearrangements in light and heavy chain DNAs. Rearranged k and λ genes of light chain contain gene segments in the order from 5' to 3' end- a short leader (L) gene segment, an intron (noncoding sequence), a joined VJ-gene segment, a second intron, and a C-gene segment (Fig. 22.18). The rearranged [...]