In this article we will discuss about the six basic rules for DNA replication. The rules are: 1. Replication is a Semi-conservative Process 2. Replication has Direction 3. Replication Starts off a Unique Point on Bacterial and Viral Chromosomes 4. Replication of Both Strands Proceeds by the Addition of Nucleotide Monomers in the 5'-3' Direction and Others. Rule # 1. [...]
In this article we will discuss about the rolling cycle method of DNA replication in φ X 174. All circular genomes do not follow the same pattern of replication described in E. coli. In some bacteriophages (phi, lambda and phi X 174), in mitochondrial chromosomes and during bacterial mating an alternative method known as the rolling circle has been demonstrated. [...]
In this article we will discuss about the introduction and mechanism of DNA replication. Introduction to DNA Replication: While presenting the double helical model of DNA, Watson and Crick had remarked, "It has not escaped our notice that the specific pairing (of bases) we have postulated suggests a possible copying mechanism for the genetic material." The complementary nature of the [...]