In this article we will discuss about the properties of cytokines (explained with diagram). 1. Cytokines are a group of low-molecular- weight regulatory proteins secreted by WBC and other cells in the body. 2. Cytokine secretion is very specific and self- limited event as because they are not usually stored as performed molecules. Cytokine synthesis is initiated by new gene [...]
In this article we will discuss about the structure of cytokines with its suitable diagram. 1. Cytokines are proteins or glycoproteins which normally have a molecular mass of less than 30 KDa. 2. Structural predictions suggest that cytokines belong to haematopoietins, included in the haematopoietin family of interleukins (2-7, 9, 11-13 and 15) GM-CSF, G-GSF, leukomia- inhibitory factor (LIF) and [...]
On the basis of principal biologic actions; cytokines are grouped under three basic categories: (i) Mediators and regulators of innate immunity: These are produced mainly by mononuclear phagocytes in response to infectious agents: Pathogen-associated molecular patterns; like bacterial lipopolysaccharides (LPS) and viral double stranded RNA (dsRNA), also bind to Toll like receptors (TLRs) on the cell surface or in endosomes [...]