This article provides a note on chloramphenicol. Chloramphenicol is a highly active, broad spectrum antibiotic with excellent pharmacokinetic properties. Source: It is obtained from Actinomyces venezuelae. It is the first antibiotic to be synthesised commercially. Chemistry: It is a derivative of di-chloroacetic acid and contains nitrobenzene moiety. It is a white or grey or yellow fine crystalline powder. It is [...]
Here is a list of nine aminoglycoside antibiotics. 1. Streptomycin: 1. Isolated from streptomyces griseus in 1943. 2. Very soluble in water. 3. Stable compared with penicillin. 4. Pure dry powder remain full potency at room temperature for at least 2 years. 5. Intestinal absorption poor. 6. Used in the treatment of enteritis. 7. Slow absorption from I/M route. 8. [...]
After reading this article we will discuss about:- 1. Chemistry of Tetracyclines 2. Classification of Tetracyclines 3. Antibacterial Spectrum 4. Bacterial Resistance 5. Mechanism of Action 6. Administration 7. Pharmacokinetics 8. Side Effects 9. Precautions 10. Therapeutic Indications 11. Dosage Regimens. Chemistry of Tetracyclines: As the name suggests, chemically tetracyclines have four partially unsaturated cyclohexane rings and are the close [...]